The site itself is pretty easy to navigate. You are able to customize various aspects of your profile. Stock profile images to select from are slim pickings. So if you want something more interesting, it's definitely best to use a personal photograph. There is a 'biography' section, but not a lot of room to write much about yourself there.
The concept behind the site is pretty cool - connecting all your sites in one central location. But there are applications that currently do that (or very similar), so it's not particularly unique. However, there is definitely potential there.
It's worth checking out for sure. And if you sign up today they can receive a free pack of about.me business cards from MOO. Check my profile out: http://about.me/mamabearalit and sign up at about.me.